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Large Advantix controls ticks including the paralysis tick (Ixodes holocylcus), brown dog tick (Rhipicephalus sanguineus ), and bush tick (Haemaphysalis longicornis. Advantix both repels and kills ticks. It is also for the treatment and prevention of fleas (Ctenocephalides) and reduces the incidence of Flea Allergy dermatitis. Advantix controls lice (Trichodectes canis, Linognathus setosus) for up to 6 weeks and repels and kills mosquitoes and sand-flies while repeling stable biting flies in dogs over 10-25 kg.